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Item Details
Title: MODULATION OF CARDIAC CALCIUM SENSITIVITY
A NEW APPROACH TO INCREASING THE STRENGTH OF THE HEART
By: J. A. Lee (Editor), David G. Allen (Editor)
Format: Hardback

List price: £120.00
Our price: £105.00
Discount:
12.5% off
You save: £15.00
ISBN 10: 0192623478
ISBN 13: 9780192623478
Availability: Usually dispatched within 1-3 weeks.
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Publisher: OXFORD UNIVERSITY PRESS
Pub. date: 18 March, 1993
Pages: 360
Description: Calcium sensitizers are a new class of drug which increases the force of contraction of the heart by increasing the calcium sensitivity of contractile proteins. Their development represents the first major innovation in the treatment of heart failure for over 200 years. Unlike other drugs in this area, they do not increase the intracellular calcium concentration and do not have the side-effects associated with that mechanism of action. These drugs offer an excitingalternative approach to the treatment of heart failure, and this volume provides an authoritative overview of the physiology, biochemistry, and clincial issues involved. It will be of interest to pharmacologists, research and clinical cardiologists, and physiologists.
Synopsis: The devlopment of calcium sensitizers represents the first major innovation in the treatment of heart failure for over 200 years. Unlike other drugs in this area, they do not increase the intracellular calcium concentration and do not have the side effects associated with that mechanism of action. These drugs offer an exciting alternative approach to the treatment of heart failure, and this volume provides an authoritative overview of the physiology, biochemistry, and clinical issues involved. It will be of particular interest to all those concerned with the treatment of heart failure.
Illustrations: numerous line illustrations, tables
Publication: UK
Imprint: Oxford University Press
Returns: Returnable
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