THE CYTOKINE NETWORK AND IMMUNE FUNCTIONS by Jacques Theze (Editor) ( 9780198501367 )

Item Details

Title:

THE CYTOKINE NETWORK AND IMMUNE FUNCTIONS

By:

Jacques Theze (Editor)

Format:

Hardback

List price:

£105.00

Our price:

£91.88

Discount:

12.5% off

You save:

£13.12

ISBN 10:

0198501366

ISBN 13:

9780198501367

Availability:

Usually dispatched within 1-3 weeks.

Delivery rates

Stock:

Currently 0 available

Publisher:

OXFORD UNIVERSITY PRESS

Pub. date:

8 July, 1999

Pages:

406

Description:

Cytokines are well characterized molecules that control the communication between cells. Their importance in immunology is very critical for the control of the quantity and of the quality of each specific response against foreign antigens (virus, bacteria, ...). When the cytokine network is mis-regulated disease can appear (autoimmunity, immunodeficiencies like in AIDS or cancer). This comprehensive treatment of this exciting area of molecular medicine presents aninformative description of the major cytokines together with coverage of their role in the different parts of the immune system and of their implication in immunopathology, and will be of great interest to medical researchers and academics in the field. Industrial researchers with an interest inimmunology will also find this book useful.

Synopsis:

The great scientific progress in our understanding of the genetics, chemistry, biology and pathophysiology of the cytokines has made clear the need for a comprehensive discussion of these molecules as part of a unified system. The Cytokine Network and Immune Functions provides just such a treatment. It represents the efforts of many of the most prominent scientists studying these molecules. Not only does it present a general discussion of each of the major cytokines or sets of cytokines; it deals in detail with how these molecules affect all aspects of immune function, and how they contribute to a wide range of pathological conditions. As the title clearly indicates, this book does not treat individual cytokines in isolation; it recognizes that they act in a complex web of synergistic and counter-regulatory effects so as to provide opportunities for the very fine control of immune responses. Cytokine biology is not only a fascinating scientific discipline, giving insight into how the immune and inflammatory systems are linked and regulated, but also it is a subject of profound importance in modern medicine.As the chapters in the section of this book entitled Cytokines in Pathology indicate, virtually all insults to the organism, be they r ste or chronic, call upon cytokine responses and virtually every disease entity has a component involving the function of cytokines. In some diseases, such as allergy and asthma and many of the autoimmune disorders, 'abnormal' cytokine responses are at the very heart of the disease process; in others, their impact may be more peripheral. There can be no doubt, however, that the study of cytokine biology has contributed greatly to the growing power of molecular medicine, transforming our approach to disease and building a new armamentarium of drugs and other treatments that promise to revolutionize our capacity to control a wide range of disease states.

Illustrations:

10 halftones, numerous line figures

Publication:

Imprint:

Oxford University Press

Returns:

Returnable