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Item Details
Title: ENTERIC INFECTIONS AND IMMUNITY
By: Lois J. Paradise (Editor), Mauro Bendinelli (Editor), Herman Friedman (Editor)
Format: Hardback

List price: £193.00


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ISBN 10: 0306452421
ISBN 13: 9780306452420
Publisher: SPRINGER SCIENCE+BUSINESS MEDIA
Pub. date: 31 May, 1996
Edition: 1996 ed.
Series: Infectious Agents and Pathogenesis
Pages: 272
Description: Provides information on the mechanisms of action of toxins, virulence factors, and mechanisms of invasion for the major groups of enteric microorganisms. This book features the studies on the effects of eukaryotic cell signaling as well as stimulation of the inflammatory response by induction and the actions of cytokines.
Synopsis: As we approach the end of this millennium, enteric diseases remain impor- tant public health problems. In many parts of the world, sanitary measures have advanced little over the last century, although some of the governments in those areas are striving to improve facilities for sanitation and to educate their people in proper handling of food, water, sewage, and other modes of transmission of pathogenic microbes. Even in highly developed countries, outbreaks of diarrheal diseases occur today. Globally, the annual morbidity from enteric infections is estimated at several billion and deaths at several million per year. In this volume, descriptions of some of these diseases, of immunity that results from them, of clinical studies that promote under- standing of individual and community immunity, of molecular factors of pathogenesis, and/or of advances in vaccine development have been pro- vided by leading researchers. At present, the application of molecular methods is enhancing the identification of protective antigens of many microorganisms. In addition, new methods for design and delivery of vac- cines are being devised. Perhaps then more effective tools for reducing at least some of these diseases will be available within the next decade. Lois J. Paradise Herman Friedman Mauro Bendinelli vii Contents Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xv LOIS J. PARADISE 1. Indigenous Microorganisms as a Host Defense 1 KENNETH H. WILSON 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. Composition of Intestinal Biota. . . . . . . . . . . . . . . . . . . . . . . . 2 3. Molecular Approaches to Determine Composition of the Biota . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 4. Role of the Host in Determining the Composition of the Biota . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Illustrations: XIX, 272 p.
Publication: US
Imprint: Kluwer Academic/Plenum Publishers
Returns: Returnable
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