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Item Details
Title: GENOME-WIDE ASSOCIATION STUDIES AND GENOMIC PREDICTION
By: Cedric Gondro (Editor), Julius van der Werf (Editor), Ben Hayes (Editor)
Format: Mixed media product

List price: £183.59


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ISBN 10: 1627034463
ISBN 13: 9781627034463
Publisher: HUMANA PRESS INC.
Pub. date: 12 June, 2013
Edition: 2013 ed.
Series: Methods in Molecular Biology 1019
Pages: 566
Description: This Methods in Molecular Biology (TM) book covers phenotypes of interest as well as design issues for GWAS, methods for storing and handling large datasets, quality control measures, haplotype inference, and imputation and statistical approaches to data analysis.
Synopsis: With the detailed genomic information that is now becoming available, we have a plethora of data that allows researchers to address questions in a variety of areas. Genome-wide association studies (GWAS) have become a vital approach to identify candidate regions associated with complex diseases in human medicine, production traits in agriculture, and variation in wild populations. Genomic prediction goes a step further, attempting to predict phenotypic variation in these traits from genomic information. Genome-Wide Association Studies and Genomic Prediction pulls together expert contributions to address this important area of study. The volume begins with a section covering the phenotypes of interest as well as design issues for GWAS, then moves on to discuss efficient computational methods to store and handle large datasets, quality control measures, phasing, haplotype inference, and imputation. Later chapters deal with statistical approaches to data analysis where the experimental objective is either to confirm the biology by identifying genomic regions associated to a trait or to use the data to make genomic predictions about a future phenotypic outcome (e.g. predict onset of disease). As part of the Methods in Molecular Biology series, chapters provide helpful, real-world implementation advice.
Illustrations: 47 Tables, black and white; 31 Illustrations, color; 36 Illustrations,
Publication: US
Imprint: Humana Press Inc.
Returns: Returnable
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