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Item Details
Title: BIOTHERMODYNAMICS PART A
Volume: Volume 455
By: Michael L. Johnson (Editor), Jo M. Holt (Editor), Gary K. Ackers (Editor)
Format: Hardback

List price: £135.00


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ISBN 10: 0123745969
ISBN 13: 9780123745965
Publisher: ELSEVIER SCIENCE PUBLISHING CO INC
Pub. date: 24 March, 2009
Edition: 454th edition
Series: Methods in Enzymology
Pages: 996
Description: Presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions.
Synopsis: In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. The use of thermodynamics in biological research is used as an "energy book-keeping system.? While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well.
Publication: US
Imprint: Academic Press Inc
Returns: Returnable
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