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Item Details
Title: GAP JUNCTIONS IN THE BRAIN
PHYSIOLOGICAL AND PATHOLOGICAL ROLES
By: Ekrem Dere (Editor)
Format: Hardback

List price: £104.00


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ISBN 10: 012415901X
ISBN 13: 9780124159013
Publisher: ELSEVIER SCIENCE PUBLISHING CO INC
Pub. date: 30 August, 2012
Pages: 304
Description: Provides neuroscience researchers and students with a single source for information that covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. This book discusses human disease conditions associated with mutations in single gap junction connexion genes.
Synopsis: Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants.
Publication: US
Imprint: Academic Press Inc
Returns: Returnable
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