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Item Details
Title: THE INSULIN-LIKE GROWTH FACTORS
STRUCTURES AND BIOLOGICAL FUNCTIONS
By: Paul N. Schofield (Editor)
Format: Hardback

List price: £98.00


We currently do not stock this item, please contact the publisher directly for further information.

ISBN 10: 0198542704
ISBN 13: 9780198542704
Publisher: OXFORD UNIVERSITY PRESS
Pub. date: 16 April, 1992
Pages: 296
Description: The insulin-like growth factors are peptides which mediate signals for division and differentiation between populations of cells. Recent exciting advances in the study of IGFs have led to insight into their role in embryogenesis, cancer and normal growth. This book reviews what is known of the structure and function of the IGFs. It covers all aspects of the subject, from the organization of IGF genes, to the clinical implications.
Synopsis: The past decade has seen an explosion in our understanding of the factors regulating cell proliferation and differentiation. One of the most exciting advances has been the recognition of the pivotal role of the peptide growth factors in these processes. The insulin-like growth factors, discovered in 1958 by Salmon and Ddaughaday, are now among the best characterized growth factors. Recent advances in knowledge of their receptors and binding proteins together with their purification and cloning have provided exciting insights into the role of these factors in the physiology of normal growth, embryonic development and areas of pathology such as wound healing and cancer. In this book an international group of contributers review the most up-to-date information on all aspects of the insulin like growth factors, and critically discuss models for IGF action in their own systems. The book will act as a source of information and ideas for researchers, and as an accessible introduction to the subject for students and clinicians.
Illustrations: halftones, line illustrations, tables
Publication: UK
Imprint: Oxford University Press
Returns: Returnable
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