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Item Details
| Title:
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EVALUATION OF DRUG CANDIDATES FOR PRECLINICAL DEVELOPMENT
PHARMACOKINETICS, METABOLISM, PHARMACEUTICS, AND TOXICOLOGY |
| By: |
Chao Han (Editor), Charles B. Davis (Editor), Binghe Wang (Editor) |
| Format: |
Hardback |
| List price:
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£110.95 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
0470044918 |
| ISBN 13: |
9780470044919 |
| Publisher: |
JOHN WILEY AND SONS LTD |
| Pub. date: |
19 January, 2010 |
| Series: |
Wiley Series in Drug Discovery and Development |
| Pages: |
290 |
| Description: |
Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. |
| Synopsis: |
Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost analysis, drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, assessing stability, ways to optimize drug formulation, toxicology and toxicokinetics, and more. Readers will understand why absorption-distribution-metabolism-excretion-toxicology (ADMET) is key in drug development. This is an enlightening reference for scientists, medicinal chemists, and others working in drug discovery. |
| Illustrations: |
Illustrations (some col.) |
| Publication: |
US |
| Imprint: |
Wiley-Blackwell |
| Returns: |
Returnable |
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