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Item Details
Title: MECHANISMS OF IMMUNOLOGICAL SELF-TOLERANCE
By: Guido Kroemer
Format: Hardback

List price: £74.00


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ISBN 10: 1570591164
ISBN 13: 9781570591167
Publisher: TAYLOR & FRANCIS INC
Pub. date: 1 January, 1994
Series: Medical Intelligence Unit
Pages: 118
Description: Reviews the multiple mechanisms that are involved in maintaining immunological self-tolerance. It presents an overall organigram of immune homeostasis, revealing the strategema of the immune system to take advantage of several tolerance-inducing mechanisms that are interconnected in series.
Synopsis: This book reviews the multiple mechanisms that are involved in maintaining immunological self-tolerance. It presents an overall organigram of immune homeostasis, revealing the strategema of the immune system to take advantage of several tolerance-inducing mechanisms that are interconnected in series. The molecular mechanisms governing each individual tolerance-inducing event are explored extensively. Topics discussed include: clonal deletion of self-reactive T and B cells, with regard to recent progress in apoptosis regulation; different types of functional activation of lymphocytes dealt with from a molecular point of view; and non-specific immnosuppression by cytokines and hormones, as well as the arguments in favour of a network control of immune function.
Publication: US
Imprint: CRC Press Inc
Returns: Non-returnable
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