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Item Details
Title: HUMAN STEM CELL TOXICOLOGY
By: James L. Sherley (Editor), Diana Anderson, Dipak Datta
Format: Hardback

List price: £169.00
Our price: £152.10
Discount:
10% off
You save: £16.90
ISBN 10: 178262421X
ISBN 13: 9781782624219
Availability: Usually dispatched within 1-3 weeks.
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Publisher: ROYAL SOCIETY OF CHEMISTRY
Pub. date: 11 August, 2016
Series: Issues in Toxicology 29
Pages: 299
Description: Presents the research, knowledge, and technology for detecting cytotoxic agents and addresses emerging new cell-based approaches for technical innovation. Targets university students, academics and industrialists in toxicology, pharmaceutical sciences, tissue and stem cell biology.
Synopsis: Toxicity against tissue stem cells (TSCs) is a major problem in drug development and environmental health science. Despite their essential function in all human cellular tissues, the nature of tissue stem cells is not fully understood. The small fraction of stem cells in tissues and the lack of specific biomarkers for their quantification present a formidable challenge to developing tools for their study and assays that can identify stem cell-toxic agents. Human Stem Cell Toxicology reveals TSC toxicity as a biomedical reality that is now well under siege by newly emerging ideas and technologies, despite these challenges. Chapters consider stem cell toxicity by environmental agents, pharmaceutical drug candidates, and marketed therapeutic medicines with adverse side effects. New insights to cellular, molecular, biochemical, and chemical mechanisms of human tissue stem cell toxicity are brought together. Experimental and theoretical treatments are of specific topics, including approaches to monitoring TSC function, newly discovered TSC types and TSC toxicity resistance mechanisms, are covered by expert authors.This book informs and champions the continued development of innovative technologies to predict the TSC toxicity of compounds before their use, whether in patients or the environment, by addressing emerging new cell-based approaches and concepts for technical innovation. This publication will be a useful reference for postgraduate students and researchers working in toxicology, pharmaceutical science, tissue cell biology and stem cell biology.
Publication: UK
Imprint: Royal Society of Chemistry
Returns: Returnable
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BIOMARKERS AND HUMAN BIOMONITORING
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COCKATIELS AND THEIR MUTATIONS AS PET AND AVIARY BIRDS (HB)
COMPUTATIONAL SYSTEMS PHARMACOLOGY AND TOXICOLOGY (HB)
CYTOCHROMES P450
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ECOTOXICOLOGY AND GENOTOXICOLOGY (HB)
ECOTOXICOLOGY AND GENOTOXICOLOGY (HB)
ECOTOXICOLOGY AND GENOTOXICOLOGY (HB)
ENVIRONMENTAL CARDIOLOGY
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EXPERIMENTAL TOXICOLOGY
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FIT FOR FAITH (PB)
HAIR IN TOXICOLOGY
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IN SILICO TOXICOLOGY (HB)
MALE-MEDIATED DEVELOPMENTAL TOXICITY
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MAMMALIAN TOXICOLOGY OF INSECTICIDES
MAMMALIAN TOXICOLOGY OF INSECTICIDES (HB)
METABOLIC PROFILING
METABOLIC PROFILING
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NANOTOXICOLOGY
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SILVER IN HEALTHCARE
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STEM CELL KINETICS
THE COMET ASSAY IN TOXICOLOGY
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TOXICOGENOMICS IN PREDICTIVE CARCINOGENICITY (HB)

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