Title:
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MECHANISMS OF LYMPHOCYTE ACTIVATION AND IMMUNE REGULATION
AUTOIMMUNITY 2000 AND BEYOND |
Volume: |
v. 8 |
By: |
Sudhir Gupta (Editor) |
Format: |
Hardback |
List price:
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£119.99 |
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ISBN 10: |
0306465701 |
ISBN 13: |
9780306465703 |
Publisher: |
SPRINGER SCIENCE+BUSINESS MEDIA |
Edition: |
2001 ed. |
Series: |
Advances in Experimental Medicine and Biology v. 490 |
Pages: |
136 |
Description: |
Reviews developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. This book covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies. |
Synopsis: |
Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. It covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies. It should be useful for immunologists, molecular biologists, rheumatologists, and clinical scientists. |
Illustrations: |
biography |
Publication: |
US |
Imprint: |
Kluwer Academic/Plenum Publishers |
Returns: |
Returnable |