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Item Details
Title: INTEGRATED STRATEGIES FOR DRUG DISCOVERY USING MASS SPECTROMETRY
By: Mike S. Lee
Format: Hardback

List price: £167.95


We currently do not stock this item, please contact the publisher directly for further information.

ISBN 10: 047146127X
ISBN 13: 9780471461272
Publisher: JOHN WILEY & SONS INC
Pub. date: 29 June, 2005
Series: Wiley Series on Pharmaceutical Science and Biotechnology: Practices,
Pages: 568
Description: The area of drug discovery has generated widespread interest, particularly with regard to the use of analytical technology for analysis. This book covers current analytical approaches, industry practices, and strategies in drug discovery. Analytical applications that require trace-mixture analysis are prominently featured.
Synopsis: New strategies and techniques for today's fast-paced discovery process Today, the pressure is on for high-throughput approaches to accelerate the generation, identification, and optimization of molecules with desirable drug properties. As traditional methods of analysis become antiquated, new analytical strategies and techniques are necessary to meet sample throughput requirements and manpower constraints. Among them, mass spectrometry has grown to be a front-line tool throughout drug discovery. Integrated Strategies for Drug Discovery Using Mass Spectrometry provides a thorough review of current analytical approaches, industry practices, and strategies in drug discovery. The topics represent current industry benchmarks in specific drug discovery activities that deal with proteomics, biomarker discovery, metabonomic approaches for toxicity screening, lead identification, compound libraries, quantitative bioanalytical support, biotransformation, reactive metabolite characterization, lead optimization, pharmaceutical property profiling, sample preparation strategies, and automation.THIS BOOK: Clearly explains how drug discovery and mass spectrometry are interconnected Discusses the uses and limitations of various types of mass spectrometry in various aspects of drug discovery Prominently features analytical applications that require trace-mixture analysis Provides industry applications and real-world examples Shares historical background information on various techniques to aid in the understanding of how and why new methods are now being employed to analyze samples
Illustrations: Illustrations
Publication: US
Imprint: John Wiley & Sons Inc
Returns: Returnable
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