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Item Details
| Title:
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MASS SPECTROMETRY IN BIOPHYSICS
CONFORMATION AND DYNAMICS OF BIOMOLECULES |
| By: |
Igor A. Kaltashov, Stephen J. Eyles |
| Format: |
Electronic book text |
| List price:
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£101.40 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
0471705160 |
| ISBN 13: |
9780471705161 |
| Publisher: |
JOHN WILEY AND SONS LTD |
| Pub. date: |
6 May, 2005 |
| Series: |
Wiley Series on Mass Spectrometry 12 |
| Pages: |
320 |
| Synopsis: |
The first systematic summary of biophysical mass spectrometry techniques Recent advances in mass spectrometry (MS) have pushed the frontiers of analytical chemistry into the biophysical laboratory. As a result, the biophysical community's acceptance of MS-based methods, used to study protein higher-order structure and dynamics, has accelerated the expansion of biophysical MS. Despite this growing trend, until now no single text has presented the full array of MS-based experimental techniques and strategies for biophysics. Mass Spectrometry in Biophysics expertly closes this gap in the literature. Covering the theoretical background and technical aspects of each method, this much-needed reference offers an unparalleled overview of the current state of biophysical MS. Mass Spectrometry in Biophysics begins with a helpful discussion of general biophysical concepts and MS-related techniques. Subsequent chapters address: * Modern spectrometric hardware * High-order structure and dynamics as probed by various MS-based methods * Techniques used to study structure and behavior of non-native protein states that become populated under denaturing conditions * Kinetic aspects of protein folding and enzyme catalysis * MS-based methods used to extract quantitative information on protein-ligand interactions * Relation of MS-based techniques to other experimental tools * Biomolecular properties in the gas phase Fully referenced and containing a helpful appendix on the physics of electrospray mass spectrometry, Mass Spectrometry in Biophysics also offers a compelling look at the current challenges facing biomolecular MS and the potential applications that will likely shape its future. |
| Illustrations: |
Drawings: 120 B&W, 0 Color |
| Publication: |
UK |
| Imprint: |
John Wiley & Sons Ltd |
| Returns: |
Non-returnable |
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