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Item Details
| Title:
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IMMUNOLOGY OF LIVER DISEASE
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| By: |
Howard C. Thomas (Editor), J. Waters (Editor) |
| Format: |
Hardback |
| List price:
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£149.99 |
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We believe that this item is permanently unavailable, and so we cannot source
it.
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| ISBN 10: |
0792389751 |
| ISBN 13: |
9780792389750 |
| Publisher: |
KLUWER ACADEMIC PUBLISHERS |
| Series: |
Immunology and Medicine v. 21 |
| Pages: |
209 |
| Description: |
Examines the role of the immune response in liver disease. This book includes introductory chapters that discuss viral immunopathology and the other autoimmune diseases. It reviews the use of immunotherapy in hepatocellular carcinoma, and the advances in the identification and characterisation of autoantibodies and their cytoplasmic antigens. |
| Synopsis: |
The role of the immune response in both the pathology of liver disease and in the modulation ofliver injury has been the subject of intense research. This book aims to present the current understanding of the involvement of the immune response in liver disease. The first chapters examine the role of the immune response in viral infections of the liver. These viruses cause hepatitis of varying severity and it is thought that many of the mechanisms responsible for liver cell injury are immunologically mediated. In addition three of these viruses, hepatitic B, C, and D, are associated with persistent infection and chronic liver disease. The role of the immune response in viral persistence is discussed. Further chapters are devoted to the three major autoimmune liver diseases which are thought to be the result of loss of tolerance to autologous liver tissue. There has been much recent research on cellular immune responses in these diseases but knowledge of the immunological processes which lead to the breakdown of tolerance and the mechanisms of tissue damage are limited.Other research has concentrated on the identification of the antigens which are the targets of this immune response. Linkage disequilibrium between MHC alleles and autoimmune diseases has suggested a role for immunogenetic factors. |
| Illustrations: |
biography |
| Publication: |
US |
| Imprint: |
Kluwer Academic Publishers |
| Returns: |
Returnable |
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