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Item Details
| Title:
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SAMPLE SIZE CALCULATIONS FOR CLUSTERED AND LONGITUDINAL OUTCOMES IN CLINICAL RESEARCH
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| By: |
Chul Ahn, Moonseoung Heo, Song Zhang |
| Format: |
Electronic book text |
| List price:
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£65.99 |
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We believe that this item is permanently unavailable, and so we cannot source
it.
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| ISBN 10: |
1466556277 |
| ISBN 13: |
9781466556270 |
| Publisher: |
TAYLOR & FRANCIS INC |
| Pub. date: |
9 December, 2014 |
| Series: |
Chapman & Hall/CRC Biostatistics Series |
| Pages: |
260 |
| Synopsis: |
Accurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study. Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies.The book focuses on issues specific to the two types of correlated outcomes: longitudinal and clustered. For clustered studies, the authors provide sample size formulas that accommodate variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas to account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the level at which to perform randomization actually becomes a design parameter. The authors show how this can greatly impact trial administration, analysis, and sample size requirement.Addressing the overarching theme of sample size determination for correlated outcomes, this book provides a useful resource for biostatisticians, clinical investigators, epidemiologists, and social scientists whose research involves trials with correlated outcomes. Each chapter is self-contained so readers can explore topics relevant to their research projects without having to refer to other chapters. |
| Illustrations: |
27 Tables, black and white; 7 Illustrations, black and white |
| Publication: |
US |
| Imprint: |
Chapman & Hall/CRC |
| Returns: |
Non-returnable |
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A celebratory, inclusive and educational exploration of Ramadan and Eid al-Fitr for both children that celebrate and children who want to understand and appreciate their peers who do.
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