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Item Details
| Title:
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CELL DEATH SIGNALING IN CANCER BIOLOGY AND TREATMENT
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| By: |
Daniel Johnson (Editor) |
| Format: |
Paperback |
| List price:
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£119.99 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
1493901079 |
| ISBN 13: |
9781493901074 |
| Publisher: |
HUMANA PRESS INC. |
| Pub. date: |
17 December, 2012 |
| Edition: |
2013 ed. |
| Series: |
Cell Death in Biology and Diseases |
| Pages: |
408 |
| Description: |
Discussing both preclinical and clinical approaches to targeted attacks on tumor cells, this is a key contribution to the fight against cancer, sharing cutting-edge research on the molecular and biological processes regulating cell death in malignant tumors. |
| Synopsis: |
A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of Cell Death Signaling in Cancer Biology and Treatment is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell death due to overexpression/hyperactivation of oncoproteins, as well as the loss of tumor suppressor proteins will be described. The potential for targeting microRNAs will be discussed. Multiple chapters will describe preclinical and clinical approaches that are currently being used to target epigenetic modifications, DNA repair pathways, and protein chaperones, as a means of provoking tumor cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed. |
| Illustrations: |
10 Tables, black and white; XVI, 408 p. |
| Publication: |
US |
| Imprint: |
Humana Press Inc. |
| Returns: |
Returnable |
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