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Item Details
Title: HOMING ENDONUCLEASES
METHODS AND PROTOCOLS
By: David R. Edgell (Editor)
Format: Paperback

List price: £92.00


We currently do not stock this item, please contact the publisher directly for further information.

ISBN 10: 1493963198
ISBN 13: 9781493963195
Publisher: HUMANA PRESS INC.
Pub. date: 19 August, 2016
Edition: Softcover reprint of the original 1st ed. 2014
Series: Methods in Molecular Biology 1123
Pages: 284
Synopsis: Homing Endonucleases: Methods and Protocols aims at providing molecular biologists with a comprehensive resource to identify and characterize homing endonucleases from genomic sequence, to deduce the biological basis of binding and cleavage specificity, as well as to provide protocols to redesign endonuclease target specificity for genome-editing applications. Engineering of designer homing endonucleases has set the stage for genome editing of complex eukaryotic genomes with a broad range of potential applications including targeted gene knockouts in model organisms and gene therapy in humans, making this book a valuable resource for future research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Homing Endonucleases: Methods and Protocols serves as a key reference for all labs studying site-specific DNA endonucleases.
Illustrations: 12 Tables, black and white; 39 Illustrations, color; 21 Illustrations,
Publication: US
Imprint: Humana Press Inc.
Returns: Returnable
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