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Item Details
Title: VENOMS TO DRUGS
VENOM AS A SOURCE FOR THE DEVELOPMENT OF HUMAN THERAPEUTICS
By: Glenn F. King (Editor), David E. Thurston, Bryan Fry
Format: Hardback

List price: £169.00
Our price: £152.10
Discount:
10% off
You save: £16.90
ISBN 10: 1849736634
ISBN 13: 9781849736633
Availability: Reprinting. This item may be subject to delays or cancellation.
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Publisher: ROYAL SOCIETY OF CHEMISTRY
Pub. date: 10 February, 2015
Series: Drug Discovery 42
Pages: 337
Description: An exciting volume that provides a comprehensive and up-to-date review on the potential of peptides and proteins from animal venoms as human therapeutics.
Synopsis: The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. This unique book provides an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms.The first text to focus on this fascinating area and bridging an important gap, this book provides the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.
Publication: UK
Imprint: Royal Society of Chemistry
Returns: Returnable
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COMPREHENSIVE BIOMARKER DISCOVERY AND VALIDATION FOR CLINICAL APPLICATION (HB)
COMPUTATIONAL APPROACHES TO NUCLEAR RECEPTORS
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DRUG DESIGN STRATEGIES
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DRUG DISCOVERY FROM NATURAL PRODUCTS
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EMERGING DRUGS AND TARGETS FOR ALZHEIMER'S DISEASE
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EXTRACELLULAR AND INTRACELLULAR SIGNALING (HB)
INTRODUCTION TO BIOLOGICAL AND SMALL MOLECULE DRUG RESEARCH AND DEVELOPMENT (HB)
ION CHANNEL DRUG DISCOVERY
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MECHANISTIC ENZYMOLOGY AND DRUG DESIGN (HB)
METABOLISM, PHARMACOKINETICS AND TOXICITY OF FUNCTIONAL GROUPS (HB)
NANOSTRUCTURED BIOMATERIALS FOR OVERCOMING BIOLOGICAL BARRIERS
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NEGLECTED DISEASES AND DRUG DISCOVERY (HB)
NEURODEGENERATION (HB)
NEW FRONTIERS IN CHEMICAL BIOLOGY
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NEW HORIZONS IN PREDICTIVE TOXICOLOGY
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NEW SYNTHETIC TECHNOLOGIES IN MEDICINAL CHEMISTRY (HB)
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ORGANIC CHEMISTRY OF DRUG DEGRADATION (HB)
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SUCCESSFUL STRATEGIES FOR THE DISCOVERY OF ANTIVIRAL DRUGS
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TRADITIONAL CHINESE MEDICINE
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