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Item Details
| Title:
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MEDICINAL CHEMISTRY APPROACHES TO PERSONALIZED MEDICINE
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| By: |
Karen Lackey (Editor), Bruce D. Roth (Editor), Raimund Mannhold |
| Format: |
Hardback |
| List price:
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£134.95 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
3527333940 |
| ISBN 13: |
9783527333943 |
| Publisher: |
WILEY-VCH VERLAG GMBH |
| Pub. date: |
18 December, 2013 |
| Series: |
Methods and Principles in Medicinal Chemistry |
| Pages: |
408 |
| Description: |
The prime knowledge resource for drug developers, this handbook contains case studies from the first generation of "personalized drugs" in cancer, neuroscience and inflammation, highlighting the challenges and opportunities of personalized medicine for pharmaceutical development. |
| Synopsis: |
Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues. Numerous case studies from the first generation of "personalized drugs" are presented, highlighting the challenges and opportunities for pharmaceutical development. While the majority of these examples are taken from the field of cancer treatment, other key emerging areas, such as neurosciences and inflammation, are also covered. With its careful balance of current and future approaches, this handbook is a prime knowledge source for every drug developer, and one that will remain up to date for some time to come.From the content: * Discovery of Predictive Biomarkers for Anticancer Drugs * Discovery and Development of Vemurafenib * Targeting Basal-Cell Carcinoma * G-Quadruplexes as Therapeutic Targets in Cancer * From Human Genetics to Drug Candidates: An Industrial Perspective on LRRK2 Inhibition as a Treatment for Parkinson's Disease * Therapeutic Potential of Kinases in Asthma * DNA Damage Repair Pathways and Synthetic Lethality * Medicinal Chemistry in the Context of the Human Genome and many more |
| Illustrations: |
illustrations |
| Publication: |
Germany |
| Imprint: |
Wiley-VCH Verlag GmbH |
| Returns: |
Returnable |
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