 |
|
|
Item Details
| Title:
|
PROTEIN-PROTEIN COMPLEXES: ANALYSIS, MODELING AND DRUG DESIGN
|
| By: |
Martin Zacharias (Editor) |
| Format: |
Paperback |
| List price:
|
£68.00 |
| Our price: |
£61.20 |
| Discount: |
|
| You save:
|
£6.80 |
|
|
|
|
|
| ISBN 10: |
1848163398 |
| ISBN 13: |
9781848163393 |
| Availability: |
Usually dispatched within 1-3 weeks.
 Delivery
rates
|
| Stock: |
Currently 0 available |
| Publisher: |
IMPERIAL COLLEGE PRESS |
| Pub. date: |
10 May, 2010 |
| Pages: |
400 |
| Description: |
Focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. This title intends to serves as a bridge between studying/analyzing protein-protein complex structures (interfaces), predicting interactions, and influencing/designing interactions. |
| Synopsis: |
Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are the driving forces for protein-protein association? How can we extract the mechanism of specific recognition from studying protein-protein interfaces? How can this knowledge be used to predict and design protein-protein interactions (interaction regions and complex structures)? What methods are currently employed to design protein-protein interactions, and how can we influence protein-protein interactions by mutagenesis and small-molecule drugs or peptide mimetics?The book consists of about 15 review chapters, written by experts, on the characterization of protein-protein interfaces, structure determination of protein complexes (by NMR and X-ray), theory of protein-protein binding, dynamics of protein interfaces, bioinformatics methods to predict interaction regions, and prediction of protein-protein complex structures (docking and homology modeling of complexes, etc.) and design of protein-protein interactions. It serves as a bridge between studying/analyzing protein-protein complex structures (interfaces), predicting interactions, and influencing/designing interactions. |
| Publication: |
UK |
| Imprint: |
Imperial College Press |
| Returns: |
Returnable |
|
|
|
 |
|
|
|
|
|
No Cheese, Please!
A fun picture book for children with food allergies - full of friendship and super-cute characters!Little Mo the mouse is having a birthday party.
|
My Brother Is a Superhero
Luke is massively annoyed about this, but when Zack is kidnapped by his arch-nemesis, Luke and his friends have only five days to find him and save the world...
|
|
|
|
|