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Item Details
Title: DIRECTED MUTAGENESIS: A PRACTICAL APPROACH
By: M. J. McPherson (Editor)
Format: Paperback

List price: £98.00


We currently do not stock this item, please contact the publisher directly for further information.

ISBN 10: 0199631409
ISBN 13: 9780199631407
Publisher: OXFORD UNIVERSITY PRESS
Pub. date: 27 June, 1991
Series: Practical Approach Series 73
Pages: 278
Description: Directed mutagenesis has emerged as an essential tool in both genetic and protein engineering by facilitating both molecular analysis and the modification of the structural and functional properties of cloned DNA sequences. This book draws together a wide range of methods for the efficient directed mutagenesis of cloned DNA sequences.
Synopsis: Directed mutagenesis has emerged as an essential tool in both genetic and protein engineering by facilitating both molecular analysis and the modification of the structural and functional properties of cloned DNA sequences. Techniques have been refined to the point where virtually any desired change or series of changes in the nucleotide sequence may be rapidly introduced. Several methods also exist for the introduction of random rather than targeted mutations, thus allowing the identification of structurally or functionally important regions that might not otherwise be detected. This book draws together a wide range of methods for the efficient directed mutagenesis of cloned DNA sequences. It provides up-to-date protocols and practical advice that should be of use to the beginner who wishes to be guided through the available approaches, and to the experienced researcher interested in exploring alternative procedures.
Illustrations: numerous halftones, line drawings and tables
Publication: UK
Imprint: Oxford University Press
Returns: Returnable
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