| Synopsis: |
The vast diversity of structures encountered among natural products is a constant challenge to the ingenuity of the organic chemist. The present volume is the eighth in the series, and the fifth devoted to stereoselective synthesis. The contributions in the book cover synthetic approaches to target molecules having adjacent quaternary carbon centers, applications of titanium-induced coupling reactions in the synthesis of diterpenes, synthesis of phosphopolyprenols, the use of anodic oxidation of phenols in the synthesis of natural products, synthesis of terpenes, bisabolones and gibberellins, applications of asymmetric Diels-Alder reactions, synthetic approaches to macrocycles, chemistry of tricarbonyl compounds and cycloisomerisations as well as sequential Michael additions in natural product synthesis. Synthetic approaches to indole alkaloids, thio-oligosaccharides, norepinephrine derivatives, carcinogenic adducts of DNA and thymosins are presented. The stereochemistry and mechanism of methylmuconate pathways are also described. The articles are written by eminent scientists and will be of interest to all researchers dealing with natural products. |