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Item Details
| Title:
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STUDIES IN NATURAL PRODUCTS CHEMISTRY
STEREOSELECTIVE SYNTHESIS |
| Volume: |
Volume 12 |
| By: |
Atta-ur-Rahman (Editor) |
| Format: |
Hardback |
| List price:
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£56.99 |
| Our price: |
£51.29 |
| Discount: |
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| You save:
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£5.70 |
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| ISBN 10: |
0444893660 |
| ISBN 13: |
9780444893666 |
| Availability: |
This item will be printed on demand and will usually be dispatched within 10 days.
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| Stock: |
Currently 0 available |
| Publisher: |
ELSEVIER SCIENCE & TECHNOLOGY |
| Pub. date: |
1 January, 1993 |
| Series: |
Studies in Natural Products Chemistry |
| Pages: |
540 |
| Description: |
Contains contributions from a number of leading natural product chemists. The syntheses of the avermectin-milbemycin family of antiparasitic agents, macrolide antibiotics, beta-lactam antibiotics, taxane diterpenes and tumour-promoting diterpenes, and 2-amino alcohols are all described. |
| Synopsis: |
Studies in Natural Products Chemistry Volume 12: Stereoselective Synthesis (Part H) reviews the stereoselective synthetic and mechanistic chemistry of bicyclomycin. It discusses chemical studies of the taxane diterpenes; the synthetic methodology for 2-amino alcohols of biological interest; and the synthesis and structure of hydroxylated indolizidines. Some of the topics covered in the book are the synthetic routes to the oxahydrindene subunit of the avermectin-milbemycin family of antiparasitic agents; isolation, structure elucidation, biosynthesis, and biological activity of the avermectins; two-stage coupling process of macrolide antibiotics synthesis; and synthesis of the rifamycin S ansa-chain compound. The complete synthesis of erythromycin A is also covered. The role of isocyanides in the synthesis of beta lactam antibiotics and the characteristics of the beta lactam antibiotics are discussed. The development of an A-Ring annulation strategy for taxane synthesis is also presented. A chapter is devoted to the advances in the synthesis of tumor-promoting diterpenes. The book can provide useful information to chemists, biologists, students, and researchers. |
| Publication: |
UK |
| Imprint: |
Elsevier Science Ltd |
| Returns: |
Returnable |
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