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Item Details
Title:
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MYOCARDIAL TISSUE ENGINEERING
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By: |
Aldo R. Boccaccini (Editor), Sian E. Harding (Editor) |
Format: |
Paperback |
List price:
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£149.00 |
We currently do not stock this item, please contact the publisher directly for
further information.
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ISBN 10: |
3642269788 |
ISBN 13: |
9783642269783 |
Publisher: |
SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG |
Pub. date: |
24 October, 2013 |
Edition: |
2011 ed. |
Series: |
Studies in Mechanobiology, Tissue Engineering and Biomaterials 6 |
Pages: |
270 |
Description: |
Myocardial tissue engineering is continuously improving. This book gives a complete analysis of the area and presents the latest advances. It covers all relevant aspects of MTE strategies, including cell sources, specific TE techniques and biomaterials used. |
Synopsis: |
Myocardial tissue engineering (MTE), a concept that intends to prolong patients' life after cardiac damage by supporting or restoring heart function, is continuously improving. Common MTE strategies include an engineered `vehicle', which may be a porous scaffold or a dense substrate or patch, made of either natural or synthetic polymeric materials. The function of the substrate is to aid transportation of cells into the diseased region of the heart and support their integration. This book, which contains chapters written by leading experts in MTE, gives a complete analysis of the area and presents the latest advances in the field. The chapters cover all relevant aspects of MTE strategies, including cell sources, specific TE techniques and biomaterials used. Many different cell types have been suggested for cell therapy in the framework of MTE, including autologous bone marrow-derived or cardiac progenitors, as well as embryonic or induced pluripotent stem cells, each having their particular advantages and disadvantages. The book covers a complete range of biomaterials, examining different aspects of their application in MTE, such as biocompatibility with cardiac cells, mechanical capability and compatibility with the mechanical properties of the native myocardium as well as degradation behaviour in vivo and in vitro. Although a great deal of research is being carried out in the field, this book also addresses many questions that still remain unanswered and highlights those areas in which further research efforts are required. The book will also give an insight into clinical trials and possible novel cell sources for cell therapy in MTE. |
Illustrations: |
X, 270 p. |
Publication: |
Germany |
Imprint: |
Springer-Verlag Berlin and Heidelberg GmbH & Co. K |
Returns: |
Returnable |
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